Shawn French, Ph.D.
Position: Research Associate
Shawn completed a Ph.D in Biophysics at the University of Guelph. He joined the Brown lab in January 2012, and is working on applying his knowledge of cell structure and membrane physicochemistry towards cutting-edge methods in antimicrobial development. Outside of the lab, Shawn builds scientific computing systems that are tailored to interfacing with analog/legacy equipment. He prefers, however, to spend his free time cooking and reading books about warlocks.
My research revolves around finding new screening phenotypes, and exploring their potential in screening for new bioactive molecules. Further, I have been creating new platforms for novel chemical-genomics screening. In increasingly high throughput, we can now assess whole genome responses to stimuli such chemical or environmental pressures.
Authors: MacNair CR, Stokes JM, French S, Myers CL, Iyer KR, Brown ED.
Reference: Bioorg Med Chem. 2016 Dec 15;24(24):6315-6319. doi: 10.1016/j.bmc.2016.09.053.
Authors: Myers CL, Li FK, Koo BM, El-Halfawy OM, French S, Gross CA, Strynadka NC, Brown ED.
Reference: J Biol Chem. 2016 Dec 9;291(50):26066-26082.
Authors: Côté JP, French S, Gehrke SS, MacNair CR, Mangat CS, Bharat A, Brown ED.
Reference: MBio. 2016 Nov 22;7(6). pii: e01714-16. doi: 10.1128/mBio.01714-16.
Authors: King AM, King DT, French S, Brouillette E, Asli A, Alexander JA, Vuckovic M, Maiti SN, Parr TR Jr, Brown ED, Malouin F, Strynadka NC, Wright GD.
Reference: ACS Chem Biol. 2016 Apr 15;11(4):864-8. doi: 10.1021/acschembio.5b00944. Epub 2016 Jan 14.
Authors: Johnston CW, Skinnider MA, Dejong CA, Rees PN, Chen GM, Walker CG, French S, Brown ED, Bérdy J, Liu DY, Magarvey NA.
Reference: Nat Chem Biol. 2016 Apr;12(4):233-9. doi: 10.1038/nchembio.2018. Epub 2016 Feb 1.
Authors: French S, Mangat C, Bharat A, Côté JP, Mori H, Brown ED.
Reference: Mol Biol Cell. 2016 Mar 15;27(6):1015-25. doi: 10.1091/mbc.E15-08-0573. Epub 2016 Jan 20.
Authors: Stokes JM, French S, Ovchinnikova OG, Bouwman C, Whitfield C, Brown ED.
Reference: Cell Chem Biol. 2016 Feb 18;23(2):267-77
Authors: Farha MA, Czarny TL, Myers CL, Worrall LJ, French S, Conrady DG, Wang Y, Oldfield E, Strynadka NC, Brown ED.
Reference: Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):11048-53. doi: 10.1073/pnas.1511751112. Epub 2015 Aug 17.