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Ph.D. Candidate

Craig Macnair, B.Sc.

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Craig Macnair, B.Sc.

Position: Ph.D. Candidate

About: Craig received his Hon B.Sc. with a specialization in Molecular Biology at the University of Western Ontario.  He is currently working towards his Ph.D. as part of the Brown lab chemical genomics group.  Outside of the lab, Craig enjoys tossing around a football and wilderness adventures.

 
mailto:macnair.craig@gmail.com
 

Publications:

Sara El Zahed, B.Sc.

Sara El Zahed, B.Sc. 

Position: Ph.D. Candidate

About: 

Sara completed her Bachelor of Science in Chemistry with a Bio-organic concentration at McGill University. She then joined the chemical genomics group at the Brown lab to pursue her graduate degree. Outside the lab, Sara enjoys playing basketball, jogging, and reading a variety of books.

 
 

Research Interest: 

Under nutrient stress, E. coli requires an additional set of 119 genes to be able to cope and to survive. The 119 genes become essential under nutrient limitation as they encode enzymes responsible for the biosynthesis of amino acids, nucleotides, and vitamins. My project aims to study the interactions between these metabolic biosynthetic pathways under nutrient limitation. Since genetic deletions of the 119 genes result in lethality under nutrient-limited conditions, I apply chemical-chemical combinations of probes and antibiotics to map out and to understand the interactions between these pathways.

Publications:

Madeline Tong, B.Sc.

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Madeline Tong, B.Sc.

Position: Ph.D. Candidate

About: Maddy completed her Hon B. Sc. at Queen's University in Life Sciences with a specialization in biomedical sciences in 2015. Outside the lab she enjoys spending her time cooking, baking and playing board games with friends.


Research Interests: Maddy currently works on understanding how different carbon sources affect the genes required for bacterial growth. 

Lindsey Carfrae, B.H.Sc.

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Lindsey Carfrae

Position: Ph.D. Candidate

About: Lindsey completed her Hon B.H.Sc. in Biomedical Discovery and Commercialization at McMaster University. She joined the Brown lab in 2016 and is currently part of the nutrient stress group. Outside of the lab, Lindsey enjoys basketball, reading, and hiking.

Kristina Klobucar, B.Sc.

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Kristina Klobucar, B.Sc. 

Position: Ph. D. Candidate

About: Kristina completed her Hon B.Sc. in Molecular Biology & Genetics at McMaster University. She joined the Brown lab in 2016 and is currently part of the outer membrane group. Outside of the lab, Kristina enjoys reading, watching cooking shows, and the outdoors.


Research Interest: Kristina is studying the Gram-negative outer membrane. She is investigating ways to potentiate Gram-positive antibiotics in Gram-negative bacteria using the principles of synthetic lethality.


Publications:

Kenneth Rachwalski, B.H.Sc.

Kenneth Rachwalski

Kenneth Rachwalski

Kenneth Rachwalski

Position: Ph.D. Candidate

About: Ken comes to us from the BDC program at McMaster University, and started his graduate work in 2017. In his spare time he adores skateboarding and ice dancing, and one day wants to explore the mountains in Peru.

 
 

Research Interest: Ken's project revolves around exploring the complicated biology of bacterial sRNAs, but he has a keen interest in all aspects of chemical biology.