Sorting out riboswitches: Fluorescence activated cell sorting was used as the basis for a novel way of creating riboswitches for E. coli cells. The method quickly and easily isolated active riboswitches from a library of candidates, as briefly outlined in the scheme.
Authors: Fowler CC, Brown ED, Li Y.
Reference: Chembiochem. 2008 Aug 11;9(12):1906-11. doi: 10.1002/cbic.200700713