Viewing entries tagged
Brent Weber

Polynuclear ruthenium complexes are effective antibiotics against Pseudomonas aeruginosa

August 14, 2022

Authors: Weber BS, Carfrae LA, Woods JJ, Klobucar K, Bigham NP., MacNair CR, Raivio TL, Wilson JJ, Brown ED.

Reference: bioRxiv 2022 August 14; doi: 10.1101/2022.08.11.503708

Genetic and Chemical Screening in Human Blood Serum Reveals Unique Antibacterial Targets and Compounds against Klebsiella pneumoniae

July 21, 2020

Authors: Weber BS, De Jong AM, Guo ABY, Dharavath S, French S, Fiebig-Comyn AA, Coombes BK, Magnolan J, Brown ED.

Reference: Cell Rep. 2020 July 21; doi: 10.1016/j.celrep.2020.107927

Mimicking the human environment in mice reveals that inhibiting biotin biosynthesis is effective against antibiotic-resistant pathogens

October 28, 2019

Authors: Carfrae LA, MacNair CR, Brown CM, Tsai CN, Weber BS, Zlitni S, Rao VN, Chun J, Junop MS, Coombes BK, Brown ED.

Reference: Nat. Microbiol. 2019 Oct 28; doi: 10.1038/s41564-019-0595-2