A cell-based approach to characterize antimicrobial compounds through kinetic dose response

December 15, 2016

Authors: MacNair CR, Stokes JM, French S, Myers CL, Iyer KR, Brown ED.
Reference: Bioorg Med Chem. 2016 Dec 15;24(24):6315-6319. doi: 10.1016/j.bmc.2016.09.053.

Identification of Two Phosphate Starvation-induced Wall Teichoic Acid Hydrolases Provides First Insights into the Degradative Pathway of a Key Bacterial Cell Wall Component.

December 9, 2016

Authors: Myers CL, Li FK, Koo BM, El-Halfawy OM, French S, Gross CA, Strynadka NC, Brown ED.
Reference: J Biol Chem. 2016 Dec 9;291(50):26066-26082.

Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase

September 1, 2015

Authors: Farha MA, Czarny TL, Myers CL, Worrall LJ, French S, Conrady DG, Wang Y, Oldfield E, Strynadka NC, Brown ED.
Reference: Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):11048-53. doi: 10.1073/pnas.1511751112. Epub 2015 Aug 17.

Characterization of Wall Teichoic Acid Degradation by the Bacteriophage ϕ29 Appendage Protein GP12 Using Synthetic Substrate Analogs

July 31, 2015

Authors: Myers CL, Ireland RG, Garrett TA, Brown ED.
Reference: J Biol Chem. 2015 Jul 31;290(31):19133-45. doi: 10.1074/jbc.M115.662866. Epub 2015 Jun 17.

Publications

A cell-based approach to characterize antimicrobial compounds through kinetic dose response

Identification of Two Phosphate Starvation-induced Wall Teichoic Acid Hydrolases Provides First Insights into the Degradative Pathway of a Key Bacterial Cell Wall Component.

Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase

Characterization of Wall Teichoic Acid Degradation by the Bacteriophage ϕ29 Appendage Protein GP12 Using Synthetic Substrate Analogs